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GLP-1 receptor agonists have transformed diabetes care, but the long-term safety of GLP-1 therapies has become an important topic as treatment continues for many years

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Extremely obese persons may have as many as four times of adipocytes, than healthy controls, each obese subject containing twice as much lipids, as a lean person

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For nearly a decade it was the most effective oral weight loss prescription available, posting around 10% mean weight loss in its key trials